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The Genetic Basis for Atrial Fibrillation

January 24, 2020


Veteran patients with atrial fibrillation will be examined for common genetic polymorphisms, and identify gene-environment interactions with risk factors for atrial fibrillation. The investigators of the study also propose opening a Veterans Affairs Atrial Fibrillation Biorepository, a resource which will collect blood and DNA samples from patients with atrial fibrillation. Patients who will participate in the study will be targeted through the VA inpatient and outpatient clinic.


Study Information

600 subjects will be enrolled in the study. The primary purpose of the trial is observation. The study began on May 25, 2017 and is estimated to be completed by May 2022.


Inclusion Criteria


  • Subjects must be at least 18 years of age, and up to 100.
  • Subjects must have a documented history of atrial fibrillation by ECG, ECHO, and or Holter monitor event recorder.
  • Subjects must be willing to give written, informed consent.


Exclusion Criteria


  • Patients with a history of AF or atrial flutter that is only associated with cardiac surgery will be excluded from the study.
  • Subjects who cannot speak English will be excluded from the study.



The study will take place at the Jesse Brown VA Medical Center, Chicago, Illinois, United States, 60612. If you have any questions, please contact Katherine A Durham, MS, APN at 312-569-6635 /


Sponsors / Collaborators

This study is sponsored by Jesse Brown VA Medical Center. The principal investigators are Katherine A Durham, MS, APN and Dawood Dabar, MD.

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